Tuning Issues
Make use of the Innodb pool (give the database memory)
Wait timeout issues/keep thread count slow (creation is cheap with MySQL!)
fsync() changes
2x the number of processors for IO threads (more like 4x)
< Move to making more content static
Dealing With Growth >
Table of Contents
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OSCON Scaling (3 years of history in five minutes or before they take me away)
, Brian Aker, OSDN
Slashdot's History of Scaling MySQL